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This article is the 3rd in a series on the synthesis of peptides. It looks at solubilising peptides and peptide storage. Peptides are supplied as lyophilised materials, which are regarded as stable compounds for shipping purposes.
Our instrumentation allows for single batch synthesis of up to 576 small scale peptides in one operation, as well as individual peptides in multigram amounts.
In this article we detail some of the design considerations we use in peptides synthesis. This article is available to view here.
Exenatide is a synthetic 39-amino acid peptide used in the treatment of insulin-treated type 2 diabetes. This GLP-1 analogue is resistant to enzymatic degradation unlike the human Glucagon-Like Peptide-1 (GLP-1) peptide.
There are many methods for analysing amino acids but at AltaBioscience, we use ion exchange chromatography with post column derivatisation which is seen as the gold standard of the available techniques