Peptide library and microarrays
In addition to our histone peptide sets and microarrays available from our catalogue peptide products, we offer a custom peptide library and microarray service for the development of libraries tailored to your specific requirements.
A well-designed peptide library can be an invaluable tool for researchers in the fields of biotechnology, pharmaceuticals, and life sciences. With our wide range of peptide library options, including synthesised peptide mixtures, Episcan peptide libraries, and peptides immobilised on slides, we are pleased to support your research for fast, efficient and cost-effective studies.
With over 50 years of experience in peptide synthesis and analysis, working with us will allow you not only to access high-quality peptide libraries, but also to benefit from our expertise and to ensure the successful completion of your project in a timely manner.
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Dealing with Alta Bioscience was a pleasure. They did not provide something we could not do ourselves – but the speed, quality and price will make them a good option next time we are short of time – and that is basically ALL the time.
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The team at Alta were incredible to work with – in dealing with them they were always pleasant, very efficient and continuously provided updates. Their services were speedy, of good quality and the team included tons of useful information.
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Peptide library options
A single peptide made with specified positions having degenerate sites or mixtures of amino acids. For example, the peptide sequence LEYASXFE where X can be a mixture of several amino acids, e.g. Ser, phosSer, Gly.
Large numbers of individual peptides
Up to 576 peptides can be produced in one synthesis batch using the AltaBioscience Episcan technology. Ideal for epitope scanning, AltaBioscience designed and built the EpiScan II instrumentation to enable the synthesis of large numbers of peptide arrays/libraries/sets at a very low cost.
- Primarily intended for screening and epitope scanning.
- From 48 to 576 peptides produced in one synthesis batch, freeze-dried, and ready for use.
- Supplied in 8 x 12 microtitre tray format, deep well microtitre trays or individually numbered 1.2 ml tubes
- Both C-terminal acids or amides in any synthesis set
- N-terminal acetylation, biotinylation, dyes etc
- Unusual amino acids can be incorporated
- QC by mass spectrometry on at least 10% of the peptides per batch
- Estimated yields of 0.5 – 2 mg of each peptide
- Directly compatible with our microarray spotting system or any other robotic device
The Episcan software used can handle either individual sequences or scan a protein, automatically generating overlapping peptides.
Peptide microarrays are produced through direct interfacing with AltaBioscience’s high-throughput Episcan peptide synthesis system. The peptides are then printed onto glass slides coated with specific substrates directly from the microtitre trays used during the peptide synthesis process. This enables efficient and accurate production of large numbers of immobilised peptides on slides for a wide range of applications, including protein-protein interactions, antibody screening and antigen-antibody studies.
- Up to 192 different peptides per slide, each peptide printed in duplicate
- Direct copy of the 96 well arrangement on the slide
- Highly specific binding allows precise peptide orientation on the surface
- The use of a spacer between the peptide and the binder molecule ensures high peptide availability
- Most of the common peptide modifications can be used in the microarray set
- Slides are compatible with most imaging systems
A range of ready-to-ship histone microarrays and sets can be purchased directly from our online shop. They have been developed to enable testing and scanning of multiple peptides for various applications. Studies where these products have been successfully applied include epigenetic studies, protein-peptide interactions, and histone peptide applications.
For more information about our peptide library and microarrays, please email us at email@example.com or call us on +44(0)1527 584495 to speak to one of our experts.
Histone peptides and microarrays
AltaBioscience stock a selection of individual histone peptides and 5 different histone peptide sets. The peptide sequences are derived from human histones H2A, H2B, H3 and H4 and include a range of modified amino acids.
AltaBioscience has provided custom synthesis of histone peptides from human H2a, H2b, H3 and H4 regions for many years, having collaborated with the original scientist who developed the idea for histone assays.
Peptide antigens for antibody generation
Suitable for both monoclonal antibody production and polyclonal antibody production, our peptide synthesis experts can assist with peptide antigen design using our epitope design software thereby suggesting antigenic peptide regions likely to provide the best immune response.
Influenza virus peptides
Although there are ways to combat influenza viruses, they have evolved to mutate frequently in order to evade the host’s immune system.
Protein and peptide tags
Protein and peptide (epitope) tag sequences are attached to proteins to facilitate easy detection and purification of expressed proteins.