Monoclonal antibody generation
AltaBioscience provides a flexible custom monoclonal antibody generation service with options to suit customer requirements. With decades of experience within our team in creating monoclonal antibodies, we act as both a consultative and commercial presence.
Certified to ISO 9001, all aspects of the work are conducted in the UK. Peptide antigen synthesis can be provided by AltaBioscience, or we can source the antigen for clients. Alternatively, the antigen can be supplied by the client. Timescale for the complete program is 3-6 months, depending on which aspects are chosen. The service is completely customisable depending on your requirements, and we aim to fulfil your needs wherever possible.
Each project is split into five stages, and the project can be terminated at the end of each stage if requested by the client.
- Flexible monoclonal antibody generation package – choose the elements you require
- All aspects of work undertaken in the UK (compliant with UK ethical review standards)
- Options to terminate the program at set stages – saving you time and money
- Ownership of all aspects of each project line resides wholly with the client
The monoclonal antibody generation process
Our monoclonal process is identified by five phases. A typical monoclonal antibody project may yield up to 10 positive wells at the fusion screening stage and, after cloning, can deliver two or three stable monoclonal antibodies. However, the number of monoclonal antibodies generated in a project cannot be guaranteed. The project is charged per line of limiting dilution cloning to allow for ultimate flexibility and for greater numbers of candidates to be brought forward past the first stage. This gives a greater degree of flexibility in comparison to being priced by a set number of hybridomas.